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View Metrics. Email alerts Article activity alert. There are already ways of stimulating brown fat's production, but it isn't easy to do. For instance, more brown fat is produced when you spend a lot of time in the cold. The new findings suggest that orexin therapies might be useful for increasing brown fat and literally melting extra calories away. Sikder says it will now also be worthwhile to examine orexin-deficient people with narcolepsy to find out whether their brown fat activity is indeed compromised.
The majority of people with narcolepsy will have normal exams. If a doctor suspects narcolepsy, the next step will be to confirm the diagnosis with sleep studies. Additional sleep disorders People with narcolepsy may have additional sleep disorders that can worsen sleepiness and other symptoms, including sleep apnea , sleepwalking, and REM sleep behavior disorder.
For example, if a patient with narcolepsy also has some sleep apnea, it is often helpful to treat the sleep apnea first, as this should produce some improvement in daytime sleepiness. If troublesome sleepiness persists, the doctor may recommend medications for the residual sleepiness caused by the narcolepsy. Obesity Many people with narcolepsy have a tendency toward being overweight. Narcolepsy may be a risk factor for diabetes because orexin plays a role in controlling blood sugar.
A study shows no link between narcolepsy and diabetes. However, more research needs to be done as older studies do suggest a link. Regardless, being overweight raises your risk of diabetes. Overweight people with narcolepsy should be aware of their blood sugar levels. A study showed that people with narcolepsy typically ate less than those without narcolepsy.
This sounds confusing, but orexin helps us eat more and lose weight at the same time. Low values may upset this balance. This could cause weight gain even though you eat less. Not eating enough further slows metabolism.
One out of every 2 people with narcolepsy shows signs of eating disorders like bulimia or anorexia. Binge eating is common. People with narcolepsy also tend to be unhappy with their bodies and want to be thinner. This can affect your mental health.
A common narcolepsy drug is Xyrem. Xyrem is made of sodium oxybate SXB which raises lipolysis. Because of this, people on SXB usually lose weight. A study showed people using SXB for 3 months lost an average of 11 pounds.
Living with a chronic disease is tough. Weight gain along with a chronic disease can impact your mental and physical health. Making lifestyle changes may slow or stop weight gain. Eat a well-balanced diet and get plenty of exercise. Daily activity will help you burn calories and boost your mood. If you are having constant bad thoughts about your body or notice a change in the way you eat, talk to your doctor right away.
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